#Core shell technology hplc code#

These associated gains in performance and reliability enable the development of high-throughput and high-resolution methods by simply implementing the right Kinetex core-shell particle for the application. The consistency of particle diameter dispersity drives column-to-column consistency and chromatographic performance. In addition, the Kinetex core-shell manufacturing process allows for greater control of the overall average particle diameter, lending to greater monodispersed particle packing. The Kinetex core-shell (superficially porous) particle technology delivers higher efficiency (N) and performance compared to columns packed with fully porous particles. The phase has demonstrated increased polar analyte retention, improved peak shape for troublesome basic analytes under typical reversed phase conditions, and a unique multi-modal interaction selectivity making it indispensable tool for multi-compound and metabolite profile screens. The new core-shell PS C18 phase is beneficial for all types of compounds (acids, bases, neutrals), but especially for the analysis of polar basic compounds.

(June 17th, 2019) – Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces the Kinetex 2.6 µm PS C18 – the eleventh selectivity in the Kinetex core-shell HPLC/UHPLC family. For more information, visit SOURCE: Phenomenex Inc.Torrance, Calif. From drug discovery and pharmaceutical development to disease diagnosis, food safety to environmental analysis, Phenomenex chromatography solutions accelerate science and help researchers improve global health and well-being.

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories. The new Kinetex core-shell columns are available in two particle sizes – 2.6- and 1.7- micron – and in variety of column dimensions. Our product development team will continue to bring even more core-shell resources to the chromatography field.' 'We're pleased to add these two new phases to the three we initially offered. 'We introduced our revolutionary Kinetex core-shell technology one year ago, and the market response and adoption rate have exceeded our expectations,' comments Jeremy Bierman, brand manager for Phenomenex.

#Core shell technology hplc code#

The new Kinetex C8 phase meets the United States Pharmacopeia (USP) specifications for Classification Code L7, enabling laboratories using L7 columns to realize the benefits of Kinetex core-shell technology while staying compliant with USP-allowable adjustments. In comparison studies with other C18 columns, this new Kinetex phase has produced differences in peak elution order and improved separation of co-eluting compounds. These columns deliver enhanced separation and peak shape of basic compounds under neutral and acidic pH conditions. The new Kinetex XB-C18 provides a unique selectivity, incorporating two iso-butyl side chains at the base of the C18 ligand to reduce secondary interactions with residual silanols.

Kinetex core-shell technology meets researchers' need to improve results and increase productivity without large capital expenditures. Kinetex XB-C18 and Kinetex C8 bring the advantages of ultra-high liquid chromatography performance (UHPLC) within standard HPLC operating pressures to a growing list of applications. Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces the addition of two new phases in its successful Kinetex core-shell HPLC/UHPLC column family.